Synthesis of novel benzofurocoumarin analogues and their anti-proliferative effect on human cancer cell lines.
نویسندگان
چکیده
The synthesis of five new tetracyclic benzofurocoumarin (benzopsoralen) analogues is described. Their inhibitory effects on the growth of three human tumor cell lines (MDA MB 231 (breast adenocarcinoma), HeLa (cervix adenocarcinoma) and TCC-SUP (bladder transitional cell carcinoma) were evaluated, and discussed in terms of structure-activity relationship.
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ورودعنوان ژورنال:
- European journal of medicinal chemistry
دوره 47 1 شماره
صفحات -
تاریخ انتشار 2012